Methacycline hydrochloride
Cat. No.：YN251047
| 产品名称: | Methacycline hydrochloride |
| CAS No.: | 3963-95-9 |
| Chemical Name: | (4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride |
| Synonyms: | 盐酸美他环素 |
| 分子量: | 478.88 |
| 分子式: | C₂₂H₂₃ClN₂O₈ |
| SMILES: | O[C@@](C(O)=C(C(C1=C2C=CC=C1O)=O)[C@](C2=C)([H])[C@@H]3O)(C(C(C(N)=O)=C4O)=O)[C@]3([H])[C@@H]4N(C)C.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Methacycline hydrochloride 是一种四环素抗生素，可以抑制细菌蛋白质的合成。Methacycline hydrochloride 是一种有效的上皮-间质转化 (EMT) 抑制剂。Methacycline hydrochloride 在体外可阻断 EMT，体内抑制纤维发生，不会直接影响 TGF-β1 Smad 信号传导。Methacycline hydrochloride 是一种抗菌剂，具有用于肺纤维化研究的潜力。 |
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Hubert, E.G., Kalmanson, G.M., Montgomerie, J.Z., et al.Activity of methacycline, related tetracyclines, and other antibiotics against various L-forms and their parent bacteria in vitroAntimicrob. Agents and Chemother.2(4),276-280(1972)
Morton, R.S., and Higson, D.W.Methacycline (rondomycin) in gonorrhoeaBrit. J. Vener. Dis42(3),175-177(1966)
McLone, D.G., Billings, T.E., Lucas, J.B., et al.Gonorrheal urethritis in men treated with one oral dose of methacyclinePublic Health Rep.83(1),87-89(1968)
