Cloxacillin sodium
Cat. No.：YN251058
| 产品名称: | Cloxacillin sodium |
| CAS No.: | 642-78-4 |
| Chemical Name: | (2S,5R,6R)-6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, monosodium salt |
| Synonyms: | |
| 分子量: | 457.86 |
| 分子式: | C₁₉H₁₇ClN₃NaO₅S |
| SMILES: | O=C(C(C(C(C=CC=C1)=C1Cl)=NO2)=C2C)N[C@H]3[C@](SC(C)4C)([H])N(C3=O)[C@H]4C(O[Na])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cloxacillin sodium 具有有效的抗菌活性，对Staphylococcus aureus25923 的最小抑菌浓度为256 mg/L。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Gibbs, D.L., and Thornsberry, C.Susceptibility of gram-negative bacteria to β-lactam antibiotics and rapid characterization of β-lactamase activityCurr. Microbiol.2(4),239-244(1979)
Sabath, L.D., Garner, C., Wilcox, C., et al.Susceptibility of Staphylococcus aureus and Staphylococcus epidermidis to 65 antibioticsAntimicrob. Agents Chemother.9(6),962-969(1976)
Okonogi, K., Noji, Y., Nakao, M., et al.The possible physiological roles of penicillin-binding proteins of methicillin-susceptible and methicillin-resistant Staphylococcus aureusJ. Infect. Chemother.1(1),50-58(1995)
Yamaguchi, A., Adachi, A., Hirata, T., et al.Conversion of cloxacillin into a progressive inhibitor of beta-lactamases by sulfonation and its activity against various types of these enzymesJ. Antibiot. (Tokyo)38(1),83-93(1985)
Craven, N., and Anderson, J.C.Therapy of experimental staphylococcal mastitis in the mouse with cloxacillin and rifampicin, alone and in combinationRes. Vet. Sci.31(3),295-300(1981)
