Thiamphenicol
Cat. No.：YN251064
CAS No. ：15318-45-3
| 产品名称: | Thiamphenicol |
| CAS No.: | 15318-45-3 |
| Chemical Name: | 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-acetamide |
| Synonyms: | 甲砜霉素; Thiophenicol; Dextrosulphenidol |
| 分子量: | 356.22 |
| 分子式: | C₁₂H₁₅Cl₂NO₅S |
| SMILES: | O=C(N[C@H](CO)[C@H](O)C1=CC=C(S(=O)(C)=O)C=C1)C(Cl)Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Thiamphenicol (Thiophenicol) 是 Chloramphenicol 的甲基磺酰基衍生物，是一种广谱抗菌类抗生素。Thiamphenicol 通过与 50S 核糖体亚基结合而起作用，使蛋白质合成被抑制并具有抑菌作用 (针对革兰氏阴性，革兰氏阳性需氧和厌氧菌)。 |
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Feder, H.M., Jr., Osier, C., and Maderazo, E.G.Chloramphenicol: A review of its use in clinical practiceRev. Infect. Dis.3(3),(1981)
Marchese, A., Debbia, E.A., Tonoli, E., et al.In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in ItalyJ. Chemother.14(6),554-561(2002)
Raymond, J., Boutros, N., and Bergeret, M.Role of thiamphenicol in the treatment of community-acquired lung infectionsMed. Trop. (Mars)64(1),33-38(2004)
