Nadifloxacin
Cat. No.：YN251070
| 产品名称: | Nadifloxacin |
| CAS No.: | 124858-35-1 |
| Chemical Name: | 9-fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid |
| Synonyms: | 那氟沙星; OPC7251 |
| 分子量: | 360.38 |
| 分子式: | C₁₉H₂₁FN₂O₄ |
| SMILES: | O=C(C1=CN2C(C)CCC3=C2C(C1=O)=CC(F)=C3N4CCC(O)CC4)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nadifloxacin(OPC7251)是广谱的氟喹诺酮类抗生素，对寻常粉刺有效。 |
| IC50和靶点: | |
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Vogt, K., Hermann, J., Blume, U., et al.Comparative activity of the topical quinolone OPC-7251 against bacteria associated with acne vulgarisEur. J. Clin. Microbiol. Infect. Dis.11(10),943-945(1992)
Yamakawa, T., Mitsuyama, J., and Hayashi, K.In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinoloneJ. Antimicrob. Chemother.49(3),455-465(2002)
Kuwahara, K., Kitazawa, T., Kitagaki, H., et al.Nadifloxacin, an antiacne quinolone antimicrobial, inhibits the production of proinflammatory cytokines by human peripheral blood mononuclear cells and normal human keratinocytesJ. Dermatol. Sci.38(1),47-55(2005)
