Ornidazole
Cat. No.：YN251074
| 产品名称: | Ornidazole |
| CAS No.: | 16773-42-5 |
| Chemical Name: | α-(chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol |
| Synonyms: | 奥硝唑; Ro 7-0207 |
| 分子量: | 219.63 |
| 分子式: | C₇H₁₀ClN₃O₃ |
| SMILES: | CC1=NC=C([N+]([O-])=O)N1CC(CCl)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ornidazole(Ro 7-0207)是5-硝基咪唑衍生物，能抗原生动物和厌氧菌。 |
| IC50和靶点: | |
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Hoffer, M., and Grunberg, E.Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted nitroimidazolesJ. Med. Chem.17(9),1019-1020(1974)
Jokipii, L., and Jokipii, A.M.Comparative evaluation of the 2-methyl-5-nitroimidazole compounds dimetridazole, metronidazole, secnidazole, ornidazole, tinidazole, carnidazole, and panidazole against Bacteroides fragilis and other bacteria of the Bacteroides fragilis groupAntimicrob. Agents Chemother.28(4),561-564(1985)
Wüst, J.Susceptibility of anaerobic bacteria to metronidazole, ornidazole, and tinidazole and routine susceptibility testing by standardized methodsAntimicrob. Agents Chemother.11(4),631-637(1977)
Majewska, A.C., Kasprzak, W., De Jonckheere, J.F., et al.Heterogeneity in the sensitivity of stocks and clones of Giardia to metronidazole and ornidazoleTrans. R. Soc. Trop. Med. Hyg.85(1),67-69(1991)
Oberländer, G., Yeung, C.H., and Cooper, T.G.Induction of reversible infertility in male rats by oral ornidazole and its effects on sperm motility and epididymal secretionsJ. Reprod. Fertil.100(2),551-559(1994)
Bone, W., Jones, N.G., Kamp, G., et al.Effect of ornidazole on fertility of male rats: Inhibition of a glycolysis-related motility pattern and zona binding required for fertilization in vitroJ. Reprod. Fertil.118(1),127-135(2000)
