Flumequine
Cat. No.：YN251090
| 产品名称: | Flumequine |
| CAS No.: | 42835-25-6 |
| Chemical Name: | 9-fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid |
| Synonyms: | 氟甲喹; R-802 |
| 分子量: | 261.25 |
| 分子式: | C₁₄H₁₂FNO₃ |
| SMILES: | O=C(C1=CN2C(C)CCC3=C2C(C1=O)=CC(F)=C3)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Flumequine (R-802) 是一种喹诺酮类抗生素，为拓扑异构酶 II (Topoisomerase II) 抑制剂，IC50值为 15 μM (3.92 μg/mL)。 |
| IC50和靶点: | [{name:"Topoisomerase II:15 μM (IC50)'}, 'Quinolone'] |
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| Solvent & Solubility: |
Rohlfing, S.R., Gerster, J.R., and Kvam, D.C.Bioevaluation of the antibacterial flumequine for urinary tract useAntimicrob. Agents Chemother.10(1),20-24(1976)
Aller-Morán, L.M., Martínez-Lobo, F.J., Rubio, P., et al.Evaluation of the in vitro activity of flumequine against field isolates of Brachyspira hyodysenteriaeRes. Vet. Sci.103,51-53(2015)
Smith, J.T.The mode of action of 4-quinolones and possible mechanisms of resistanceJ. Antimicrob. Chemother.18 (Suppl. D),21-29(1986)
