Clinafloxacin hydrochloride
Cat. No.：YN251095
| 产品名称: | Clinafloxacin hydrochloride |
| CAS No.: | 105956-99-8 |
| Chemical Name: | 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, monohydrochloride |
| Synonyms: | 克林沙星盐酸盐; AM 1091 hydrochloride; CI 960 hydrochloride; PD127391 hydrochloride |
| 分子量: | 402.25 |
| 分子式: | C₁₇H₁₈Cl₂FN₃O₃ |
| SMILES: | O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CC(N)CC4)=C3Cl)C1=O)O.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Clinafloxacin hydrochloride (AM 1091 hydrochloride) 是一种高效广谱的氟喹诺酮类抗生素，对革兰氏阳性、革兰氏阴性和厌氧菌均有体外抗菌活性。Clinafloxacin hydrochloride 对肺炎链球菌有抑制作用，对其 parC-gyrA 突变体的MIC为 1 μg/ml。 |
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Takei, M., Fukuda, H., Kishii, R., et al.Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibitionAntimicrob. Agents Chemother.45(12),3544-3547(2001)
Weigel, L.M., Anderson, G.J., and Tenover, F.C.DNA gyrase and topoisomerase IV mutations associated with fluoroquinolone resistance in Proteus mirabilisAntimicrob. Agents Chemother.46(8),2582-2587(2002)
