Ceftazidime pentahydrate
Cat. No.：YN251104
| 产品名称: | Ceftazidime pentahydrate |
| CAS No.: | 78439-06-2 |
| Chemical Name: | 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-pyridinium, pentahydrate |
| Synonyms: | GR20263 pentahydrate |
| 分子量: | 636.65 |
| 分子式: | C₂₂H₃₂N₆O₁₂S₂ |
| SMILES: | O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N\OC(C)(C(O)=O)C)=O)[C@@]3([H])SCC(C[N+]4=CC=CC=C4)=C(C([O-])=O)N13.[5H2O] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ceftazidime pentahydrate (GR20263 pentahydrate) 是第三代头孢菌素，可静脉内或肌肉给药。Ceftazidime pentahydrate 具有广泛的针对革兰氏阳性和革兰氏阴性需氧细菌的体外活性。Ceftazidime pentahydrate 对肠杆菌科 (包括 β-内酰胺酶阳性菌株) 特别有效，并且对大多数 β-内酰胺酶具有抗水解作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Acred, P., Ryan, D.M., Sowa, M.A., et al.The in-vivo antibacterial activity of ceftazidime (Gr 20263)—a comparison with other new β-lactam antibiotics and gentamicinJ. Antimicrob. Chemother.8(Suppl. B),247-255(1981)
Fontana, R., Cornaglia, G., Ligozzi, M., et al.The final goal: Penicillin-binding proteins and the target of cephalosporinsClin. Microbiol. Infect.6(Suppl. 3),34-40(2000)
