Mafenide
Cat. No.：YN251107
CAS No. ：138-39-6
| 产品名称: | Mafenide |
| CAS No.: | 138-39-6 |
| Chemical Name: | 4-(aminomethyl)-benzenesulfonamide |
| Synonyms: | 磺胺米隆 |
| 分子量: | 186.23 |
| 分子式: | C₇H₁₀N₂O₂S |
| SMILES: | O=S(C1=CC=C(CN)C=C1)(N)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mafenide 是一种有效的磺酰胺类抗菌剂，可用于烧伤创面。Mafenide 通过抑制核苷酸合成，对革兰氏阳性和革兰氏阴性生物（包括铜绿假单胞菌）均具有活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Rodgers, G.L., Mortensen, J.E., Fisher, M.C., et al.In vitro susceptibility testing of topical antimicrobial agents used in pediatric burn patients: Comparison of two methodsJ. Burn Care Rehabil.18(5),406-410(1997)
Glasser, J.S., Guymon, C.H., Mende, K., et al.Activity of topical antimicrobial agents against multidrug-resistant bacteria recovered from burn patientsBurns36(8),1172-1184(2010)
Fox, C.L., Jr., Sampath, A.C., and Stanford, J.W.Virulence of Pseudomonas infection in burned rats and mice. Comparative efficacy of silver sulfadiazine and mafenideArch. Surg.101(4),508-512(1970)
Fidan, İ., Salmas, R.E., Arslan, M., et al.Carbonic anhydrase inhibitors: Design, synthesis, kinetic, docking and molecular dynamics analysis of novel glycine and phenylalanine sulfonamide derivativesBioorg. Med. Chem.23(23),7353-7358(2015)
