Dirithromycin
Cat. No.：YN251112
| 产品名称: | Dirithromycin |
| CAS No.: | 62013-04-1 |
| Chemical Name: | (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-7-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3-ethyl-2,10-dihydroxy-15-[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-4,1 |
| Synonyms: | 地红霉素; LY237216 |
| 分子量: | 835.07 |
| 分子式: | C₄₂H₇₈N₂O₁₄ |
| SMILES: | CC1[C@@]([C@](O)([C@H](OC([C@@H]2C)=O)CC)C)([H])O[C@H](COCCOC)N[C@@]1([H])[C@](C[C@@](O)([C@@H]([C@@H](C)[C@]2([H])O[C@@](O[C@@H](C)[C@@H]3O)([H])C[C@@]3(C)OC)O[C@@](O[C@H](C)C[C@@H]4N(C)C)([H])[C@@H]4O)C)([H])C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dirithromycin(LY 237216)是大环内酯类糖肽抗生素，能与细菌核糖体70S中的50S亚基相结合。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Hardy, D.J., Hensey, D.M., Beyer, J.M., et al.Comparative in vitro activities of new 14-, 15-, and 16-membered macrolidesAntimicrob. Agents Chemother.32(11),1710-1719(1988)
Westphal, J.F.Macrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: An update focused on clarithromycin, azithromycin and dirithromycinBr. J. Clin. Pharmacol.50(4),285-295(2000)
