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Ceftibuten dihydrate

Cat. No.:YN251117

  • CAS No. :118081-34-8

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    • 参考文献
    • 产品名称: Ceftibuten dihydrate
      CAS No.: 118081-34-8
      Chemical Name: (6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-4-carboxy-1-oxo-2-buten-1-yl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, dihydrate
      Synonyms:头孢布烯二水合物; Sch-39720 dihydrate
      分子量:446.46
      分子式:C₁₅H₁₈N₄O₈S₂
      SMILES:O=C(C(N12)=CCS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=C\CC(O)=O)=O)C1=O)O.O.O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Ceftibuten (Sch39720) dihydrate 是一种具有口服活性的头孢菌素,在体外对多种革兰氏阴性和某些革兰氏阳性病原体具有较强的抗菌活性。
      IC50和靶点:
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    • Bauernfeind, A.Ceftibuten and bactericidal kinetics. Comparative in vitro activity against Enterobacteriaceae producing extended spectrum β-lactamasesDiagn. Microbiol. Infect. Dis.14(1),89-92(1991)

      Jones, R.N., and Barry, A.L.Antimicrobial activity, spectrum, and recommendations for disk diffusion susceptibility testing of ceftibuten (7432-S; SCH 39720), a new orally administered cephalosporinAntimicrob. Agents Chemother.32(10),1576-1582(1988)

      Onyeji, C.O., Nicolau, D.P., Nightingale, C.H., et al.Optimal times above MICs of ceftibuten and cefaclor in experimental intra-abdominal infectionsAntimicrob. Agents Chemother.38(5),1112-1117(1994)

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