Rufloxacin hydrochloride
Cat. No.：YN251161
| 产品名称: | Rufloxacin hydrochloride |
| CAS No.: | 106017-08-7 |
| Chemical Name: | 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid, monohydrochloride |
| Synonyms: | MF-934 hydrochloride |
| 分子量: | 399.87 |
| 分子式: | C₁₇H₁₉ClFN₃O₃S |
| SMILES: | O=C(C(C1=O)=CN2CCSC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rufloxacin hydrochloride (MF-934 hydrochloride) 是一种喹诺酮类抗菌剂，作用于人单核细胞，抑制B细胞分化， 且制剂拓扑异构酶抑。 |
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Piddock, L.J.V., Panchal, S., and Norte, V.Comparison of the mechanism of action and resistance of two new fluoroquinolones, rufloxacin and MF961 with those of ofloxacin and fleroxacin in Gram-negative and Gram-positive bacteriaJ. Antimicrob. Chemother.31(6),855-863(1993)
Cecchetti, V., Fravolini, A., Fringuelli, R., et al.Quinolonecarboxylic acids. 2. Synthesis and antibacterial evaluation of 7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acidsJ. Med. Chem.30(3),465-473(1987)
Fabbri, S., Broggini, M., Pagella, P., et al.The inhibition of supercoiling activity of DNA gyrase from Micrococcus luteus caused by rufloxacin (MF 934) and MF 961J. Antimicrob. Chemother.27(5),687-689(1991)
Bonina, L., Carbone, M., Mastroeni, P., et al.Effects of rufloxacin in Salmonella typhimurium infection in miceJ. Chemother.4(6),353-357(1992)
