Acetohydroxamic acid
Cat. No.：YN251264
CAS No. ：546-88-3
| 产品名称: | Acetohydroxamic acid |
| CAS No.: | 546-88-3 |
| Chemical Name: | N-hydroxy-acetamide |
| Synonyms: | 乙酰氧肟酸; AHA |
| 分子量: | 75.07 |
| 分子式: | C₂H₅NO₂ |
| SMILES: | CC(NO)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Acetohydroxamic acid (AHA) 是一种有效的不可逆细菌和植物尿素酶抑制剂，可用于研究慢性尿路感染。 |
| IC50和靶点: | |
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Fishbein, W.N., and Carbone, P.P.Urease Catalysis. II. Inhibition of the enzyme by hydroxyurea, hydroxylamine, and acetohydroxamic acidJ. Biol. Chem.240(6),2407-2414(1965)
Downey, J.A., Nickel, J.C., Clapham, L., et al.In vitro inhibition of struvite crystal growth by acetohydroxamic acidBr. J. Urol.70(4),355-359(1992)
Phillips, K., Munster, D.J., Allardyce, R.A., et al.Antibacterial action of the urease inhibitor acetohydroxamic acid on Helicobacter pyloriJ. Clin. Pathol.46(4),372-373(1993)
Krawiec, D.R., Osborne, C.A., Leininger, J.R., et al.Effect of acetohydroxamic acid on dissolution of canine struvite urolithsAm. J. Vet. Res.45(7),1266-1275(1984)
Ohta, T., Shibata, H., Kawamori, T., et al.Marked reduction of Helicobacter pylori-induced gastritis by urease inhibitors, acetohydroxamic acid and flurofamide, in Mongolian gerbilsBiochem. Biophys. Res. Commun.285(3),728-733(2001)
