Cefuroxime sodium
Cat. No.:YN251272
产品名称: | Cefuroxime sodium |
CAS No.: | 56238-63-2 |
Chemical Name: | (6R,7R)-3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt |
Synonyms: | 头孢呋辛钠 |
分子量: | 446.37 |
分子式: | C₁₆H₁₅N₄NaO₈S |
SMILES: | O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)O[Na] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Cefuroxime sodium 是一种具有口服活性的第二代头孢菌素抗生素 (antibiotic),增加了对乳酸酶 (β-lactamase) 的稳定性。Cefuroxime sodium 具有广谱的抑制活性,对革兰氏阳性菌和革兰氏阴性菌都有效。 |
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O'Callaghan, C.H., Sykes, R.B., Griffiths, A., et al.Cefuroxime, a new cephalosporin antibiotic: Activity in vitroAntimicrob. Agents Chemother.9(3),511-519(1976)
Curtis, N.A.C., Hughes, J.M., and Ross, G.W.Inhibition of peptidoglycan cross-linking in growing cells of Escherichia coli by penicillins and cephalosporins, and its prevention by R factor-mediated beta-lactamaseAntimicrob. Agents Chemother.9(2),208-213(1976)
Richmond, M.H., and Wotton, S.Comparative study of seven cephalosporins: Susceptibility to beta-lactamases and ability to penetrate the surface layers of Escherichia coliAntimicrob. Agents Chemother.10(2),219-222(1976)
Ryan, D.M., O'Callaghan, C.H., and Muggleton, P.W.Cefuroxime, a new cephalosporin antibiotic: Activity in vivoAntimicrob. Agents Chemother.9(3),520-525(1976)
Masika, W.G., O'Meara, W.P., Holland, T.L., et al.Contribution of urinary tract infection to the burden of febrile illnesses in young children in rural KenyaPLoS One12(3),e0174199(2017)