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Cefuroxime sodium

Cat. No.:YN251272

  • CAS No. :56238-63-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Cefuroxime sodium
      CAS No.: 56238-63-2
      Chemical Name: (6R,7R)-3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt
      Synonyms:头孢呋辛钠
      分子量:446.37
      分子式:C₁₆H₁₅N₄NaO₈S
      SMILES:O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)O[Na]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Cefuroxime sodium 是一种具有口服活性的第二代头孢菌素抗生素 (antibiotic),增加了对乳酸酶 (β-lactamase) 的稳定性。Cefuroxime sodium 具有广谱的抑制活性,对革兰氏阳性菌和革兰氏阴性菌都有效。
      IC50和靶点:
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    • O'Callaghan, C.H., Sykes, R.B., Griffiths, A., et al.Cefuroxime, a new cephalosporin antibiotic: Activity in vitroAntimicrob. Agents Chemother.9(3),511-519(1976)

      Curtis, N.A.C., Hughes, J.M., and Ross, G.W.Inhibition of peptidoglycan cross-linking in growing cells of Escherichia coli by penicillins and cephalosporins, and its prevention by R factor-mediated beta-lactamaseAntimicrob. Agents Chemother.9(2),208-213(1976)

      Richmond, M.H., and Wotton, S.Comparative study of seven cephalosporins: Susceptibility to beta-lactamases and ability to penetrate the surface layers of Escherichia coliAntimicrob. Agents Chemother.10(2),219-222(1976)

      Ryan, D.M., O'Callaghan, C.H., and Muggleton, P.W.Cefuroxime, a new cephalosporin antibiotic: Activity in vivoAntimicrob. Agents Chemother.9(3),520-525(1976)

      Masika, W.G., O'Meara, W.P., Holland, T.L., et al.Contribution of urinary tract infection to the burden of febrile illnesses in young children in rural KenyaPLoS One12(3),e0174199(2017)

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