Chlortetracycline
Cat. No.：YN251296
CAS No. ：57-62-5
| 产品名称: | Chlortetracycline |
| CAS No.: | 57-62-5 |
| Chemical Name: | (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide |
| Synonyms: | 氯四环素; 7-Chlorotetracycline |
| 分子量: | 478.88 |
| 分子式: | C₂₂H₂₃ClN₂O₈ |
| SMILES: | O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4Cl)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Chlortetracycline (7-Chlorotetracycline) 是一种特异性的有效钙离子载体抗生素, 抑制氨酰 tRNA 结合到核糖体。 |
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Chopra, I., Hawkey, P.M., and Hinton, M.Tetracyclines, molecular and clinical aspectsJ. Antimicrob. Chemother.29(3),245-277(1992)
Paine, T.F., Jr., Collins, H.S., and Finland, M.Bacteriologic studies on aureomycinJ. Bacteriol.56(4),489-497(1948)
Cacciapuoti, A., Moss, E., Jr., Menzel, F., Jr., et al.In vitro and in vivo characterization of novel 8-methoxy derivatives of chlortetracyclineJ. Antibiot. (Tokyo)40(10),1426-1430(1987)
White, J.R., and Pearce, F.L.Characterization of chlortetracycline (aureomycin) as a calcium ionophoreBiochemistry21(24),6309-6312(1982)
Cerella, C., Mearelli, C., De Nicola, M., et al.Analysis of calcium changes in endoplasmic reticulum during apoptosis by the fluorescent indicator chlortetracyclineAnn. N. Y. Acad. Sci.1099,490-493(2007)
