Tazobactam
Cat. No.:YN251315
产品名称: | Tazobactam |
CAS No.: | 89786-04-9 |
Chemical Name: | (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 4,4-dioxide |
Synonyms: | 他唑巴坦; CL-298741; YTR-830H |
分子量: | 300.29 |
分子式: | C₁₀H₁₂N₄O₅S |
SMILES: | O=C([C@@H]([C@@](CN1N=NC=C1)(C)S([C@]2([H])C3)(=O)=O)N2C3=O)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tazobactam是一种β-内酰胺酶抑制剂, 具有抗菌活性。 |
IC50和靶点: | |
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Drawz, S.M., and Bonomo, R.A.Three decades of β-lactamase inhibitorsClin. Microbiol. Rev.23(1),160-201(2010)
Jones, R.N., Pfaller, M.A., Fuchs, P.C., et al.Piperacillin/tazobactam (YTR 830) combination. Comparative antimicrobial activity against 5889 recent aerobic clinical isolates and 60 Bacteroides fragilis group strainsDiagn. Microbiol. Infect. Dis.12(6),489-494(1989)
Craig, W.A., and Andes, D.R.In vivo activities of ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum β-lactamases, in the thighs of neutropenic miceAntimicrob. Agents Chemother.57(4),1577-1582(2013)