Isoconazole nitrate
Cat. No.：YN251320
| 产品名称: | Isoconazole nitrate |
| CAS No.: | 24168-96-5 |
| Chemical Name: | 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole, mononitrate |
| Synonyms: | 硝酸异康唑 |
| 分子量: | 479.14 |
| 分子式: | C₁₈H₁₅Cl₄N₃O₄ |
| SMILES: | ClC1=C(COC(C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)C(Cl)=CC=C1.O[N+]([O-])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Isoconazole nitrate是一种广谱抗菌剂, 高效抗真菌和革兰氏阳性菌。 |
| IC50和靶点: | |
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Hernández Molina, J.M., Llosá, J., Martinez Brocal, A., et al.In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp.Mycopathologia118(1),15-21(1992)
Godefroi, E.F., Heeres, J., Van Cutsem, J., et al.The preparation and antimycotic properties of derivatives of 1-phenethylimidazoleJ. Med. Chem.12(5),784-791(1969)
Czaika, V.A., Siebenbrock, J., Czekalla, F., et al.Reactive oxygen species and the bacteriostatic and bactericidal effects of isoconazole nitrateMycoses56(Suppl 1),16-22(2013)
Kinobe, R.T., Dercho, R.A., Vlahakis, J.Z., et al.Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugsJ. Pharmacol. Exp. Ther.319(1),277-284(2006)
