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4-Aminosalicylic acid

Cat. No.:YN251424

  • CAS No. :65-49-6

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    • 生物活性
    • 参考文献
    • 产品名称: 4-Aminosalicylic acid
      CAS No.: 65-49-6
      Chemical Name: 4-amino-2-hydroxy-benzoic acid
      Synonyms:para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate
      分子量:153.14
      分子式:C₇H₇NO₃
      SMILES:O=C(O)C1=CC=C(N)C=C1O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 4-Aminosalicylic acid 是具有口服活性的抗生素,可用于肺结核病的研究。
      IC50和靶点:
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      In Vivo:
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    • Youmans, G.P., Raleigh, G.W., and Youmans, A.S.The tuberculostatic action of para-aminosalicylic acidJ. Bacteriol.54(4),409-416(1947)

      Chakraborty, S., Gruber, T., Barry, C.E., III, et al.Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosisScience339(6115),88-91(2013)

      Peng, D., Li, J., Deng, Y., et al.Sodium para-aminosalicylic acid inhibits manganese-induced NLRP3 inflammasome-dependent pyroptosis by inhibiting NF-κB pathway activation and oxidative stressJ. Neuroinflammation17(1),343(2020)

      Terai, T., Ito, H., Kikuchi, K., et al.Salicylic-acid derivatives as antennae for ratiometric luminescent probes based on lanthanide complexesChemistry18(24),7377-7381(2012)

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