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Demethoxycurcumin

Cat. No.:YN251430

  • CAS No. :22608-11-3

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    • 参考文献
    • 产品名称: Demethoxycurcumin
      CAS No.: 22608-11-3
      Chemical Name: 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1E,6E-heptadiene-3,5-dione
      Synonyms:去甲氧基姜黄素; Curcumin II; Desmethoxycurcumin; Monodemethoxycurcumin
      分子量:338.35
      分子式:C₂₀H₁₈O₅
      SMILES:O=C(CC(/C=C/C1=CC=C(O)C=C1)=O)/C=C/C2=CC=C(O)C(OC)=C2.[(E)].[(E)]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 脱甲氧姜黄素(Demethoxycurcumin)是姜黄素的一种主要活性成分,已被证明有抗炎症和对癌细胞毒性作用。
      IC50和靶点:
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    • Sandur, S.K., Pandley, M.K., Ahn, K.S., et al.Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanismCarcinogenesis28(8),1765-1773(2007)

      Ryu, M.J., Cho, M., Song, J.Y., et al.Natural derivatives of curcumin attenuate the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300Biochem. Biophys. Res. Commun.377(4),1304-1308(2008)

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