Verbascoside
Cat. No.:YN251433
CAS No. :61276-17-3
产品名称: | Verbascoside |
CAS No.: | 61276-17-3 |
Chemical Name: | 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate] |
Synonyms: | 麦角甾苷; Acteoside; Kusaginin; TJC160 |
分子量: | 624.59 |
分子式: | C₂₉H₃₆O₁₅ |
SMILES: | O[C@@H]([C@H](OCCC1=CC(O)=C(O)C=C1)O2)[C@H]([C@@H]([C@H]2CO)OC(/C=C/C3=CC(O)=C(O)C=C3)=O)O[C@@](O[C@@H](C)[C@H](O)[C@H]4O)([H])[C@@H]4O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Verbascoside 是从Lantana camara中得到的糖苷类物质,为 ATP 竞争性的PKC抑制剂,IC50值为 25 µM,具有抗肿瘤,抗炎,抗神经性疼痛等作用。 |
IC50和靶点: | [{name:"PKC:25 μM (IC50)"}] |
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Sheng, G.Q., Zhang, J.R., Pu, X.P., et al.Protective effect of verbascoside on 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cellsEur. J. Pharmacol.451(2),119-124(2002)
Herbert, J.M., Maffrand, J.P., Toubi, K., et al.Verbascoside isolated from Lantana camara, an inhibitor of protein kinase CJ. Nat. Prod.54(6),1595-1600(1991)
Rigano, D., Formisano, C., Basile, A., et al.Antibacterial activity of flavonoids and phenylpropanoids from Marrubium globosum ssp. libanoticumPhytother. Res.21(4),395-397(2007)
Li, J., Zheng, Y., Zhou, H., et al.Differentiation of human gastric adenocarcinoma cell line MGc80-3 induced by verbascosidePlanta Med.63(6),499-502(1997)
Mazzon, E., Esposito, E., Di Paola, R., et al.Effects of verbascoside biotechnologically produced by Syringa vulgaris plant cell cultures in a rodent model of colitisNaunyn Schmiedebergs Arch. Pharmacol.380(1),79-94(2009)