Sanguinarine chloride
Cat. No.：YN251434
| 产品名称: | Sanguinarine chloride |
| CAS No.: | 5578-73-4 |
| Chemical Name: | 13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, monochloride |
| Synonyms: | 氯化血根碱; Sanguinarin chloride; Sanguinarium chloride; Pseudochelerythrine chloride |
| 分子量: | 367.78 |
| 分子式: | C₂₀H₁₄ClNO₄ |
| SMILES: | C[N+]1=CC2=C3C(OCO3)=CC=C2C(C=CC4=C5)=C1C4=CC6=C5OCO6.[Cl-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sanguinarine (Sanguinarin) chloride 是一种来源于Sanguinaria Canadensis的生物碱，可通过激活活性氧 (ROS) 的产生来刺激细胞凋亡。Sanguinarine 诱导的细胞凋亡与 JNK 和 NF-κB 的活化有关。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Ziegler, J., and Facchini, P.J.Alkaloid biosynthesis: Metabolism and traffickingAnnu. Rev. Plant Biol.59,735-769(2008)
Gupta, S.C., Kim, J.H., Prasad, S., et al.Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticalsCancer Metastasis Rev.29(3),405-434(2010)
