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Sclareolide

Cat. No.:YN251445

  • CAS No. :564-20-5

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    • 生物活性
    • 参考文献
    • 产品名称: Sclareolide
      CAS No.: 564-20-5
      Chemical Name: (3aR,5aS,9aS,9bR)-decahydro-3a,6,6,9a-tetramethyl-naphtho[2,1-b]furan-2(1H)-one
      Synonyms:香紫苏内酯,Norambreinolide
      分子量:250.38
      分子式:C₁₆H₂₆O₂
      SMILES:O=C1C[C@@]2([H])[C@](CC[C@@]3([H])C(C)(C)CCC[C@@]32C)(C)O1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Sclareolide 是从Salvia sclarea的花中分离出来的,具有抗菌和细胞毒性作用。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Chen, S., Wang, Y., Zhang, W.L., et al.Sclareolide enhances gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancerMol. Med. Rep.15(4),1461-1470(2017)

      Ma, M., Feng, J., Li, R., et al.Synthesis and antifungal activity of ethers, alcohols, and iodohydrin derivatives of sclareol against phytopathogenic fungi in vitroBioorg. Med. Chem. Lett.25(14),2773-2777(2015)

      Chen, Q., Tang, K., and Guo, Y.Discovery of sclareol and sclareolide as filovirus entry inhibitorsJ. Asian Nat. Prod. Res.22(5),464-473(2020)

      Kim, C.S., Oh, J., Subedi, L., et al.Structural characterization of terpenoids from Abies holophylla using computational and statistical methods and their biological activitiesJ. Nat. Prod.81(8),1795-1802(2018)

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