Cordycepin
Cat. No.：YN251460
CAS No. ：73-03-0
| 产品名称: | Cordycepin |
| CAS No.: | 73-03-0 |
| Chemical Name: | 3'-deoxy-adenosine |
| Synonyms: | 虫草素; 3'-Deoxyadenosine |
| 分子量: | 251.24 |
| 分子式: | C₁₀H₁₃N₅O₃ |
| SMILES: | OC[C@@H]1C[C@H]([C@H](N2C=NC3=C2N=CN=C3N)O1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cordycepin (3'-Deoxyadenosine) 是从冬虫夏草中分离的一种核苷衍生物，在类风湿性关节炎滑膜成纤维细胞 (RASF) 中，抑制 IL-1β 诱导的MMP-1和MMP-3表达，这种作用存在剂量依赖性。Cordycepin 通过抑制细菌的腺苷激酶杀死结核分枝杆菌。 |
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Cunningham, K.G., Manson, W., Spring, F.S., et al.Cordycepin, a metabolic product isolated from cultures of Cordyceps militaris (Linn.) LinkNature166(4231),949(1950)
Wong, Y.Y., Moon, A., Duffin, R., et al.Cordycepin inhibits protein synthesis and cell adhesion through effects on signal transductionJ. Biol. Chem.285(4),2610-2621(2010)
Cory, J.G., Suhadolnik, R.J., Resnick, B., et al.Incorporation of cordycepin (3'-deoxyadenosine) into ribonucleic acid and deoxyribonucleic acid of human tumor cellsBiochim. Biophys. Acta103(4),646-653(1965)
Zhou, X., Meyer, C.U., Schmidtke, P., et al.Effect of cordycepin on interleukin-10 production of human peripheral blood mononuclear cellsEur. J. Pharmacol.453(2-3),309-317(2002)
Sugar, A.M., and McCaffrey, R.P.Antifungal activity of 3'-deoxyadenosine (cordycepin)Antimicrob. Agents Chemother.42(6),1424-1427(1998)
