Isoimperatorin
Cat. No.：YN251461
| 产品名称: | Isoimperatorin |
| CAS No.: | 482-45-1 |
| Chemical Name: | 4-[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one |
| Synonyms: | 异欧前胡素 |
| 分子量: | 270.28 |
| 分子式: | C₁₆H₁₄O₄ |
| SMILES: | O=C1C=CC2=C(OC/C=C(C)/C)C3=C(OC=C3)C=C2O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Isoimperatorin 是Angelica dahurica根的甲醇提取物，有效抑制乙酰胆碱酯酶 (AChE)，IC50为 74.6 μM。 |
| IC50和靶点: | |
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Cai, Y., Bennett, D., Nair, R.V., et al.Inhibition and inactivation of murine hepatic ethoxy- and pentoxyresorufin O-dealkylase by naturally occurring coumarinsChem. Res. Toxicol.6(6),872-879(1993)
Cai, Y., Baer-Dubowska, W., Ashwood-Smith, M., et al.Inhibitory effects of naturally occurring coumarins on the metabolic activation of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured mouse keratinocytesCarcinogenesis18(1),215-222(1997)
Pokaharel, Y.R., Han, E.H., Kim, J.Y., et al.Potent protective effect of isoimperatorin against aflatoxin B1-inducible cytotoxicity in H4IIE cells: Bifunctional effects on glutathione S-transferase and CYP1ACarcinogenesis27(12),2483-2490(2006)
