Lycorine hydrochloride
Cat. No.：YN251463
| 产品名称: | Lycorine hydrochloride |
| CAS No.: | 2188-68-3 |
| Chemical Name: | Licorin Hydrochloride; 3,3a-Didehydrolycoran-1α,2β-diol Hydrochloride; (1α,2β)- 3,12-Didehydro-9,10-[methylenebis(oxy)]-galanthan-1,2-diol; 2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol Hydrochloride; (1S,2S,12bS |
| Synonyms: | 石蒜碱 |
| 分子量: | 323.77 |
| 分子式: | C₁₆H₁₈ClNO₄ |
| SMILES: | O[C@@H]1[C@@H](O)C=C(CC2)[C@@]3([H])N2CC4=C([C@@]31[H])C=C(OCO5)C5=C4.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lycorine hydrochloride 是石蒜的主要活性成分，也是黑色素瘤血管生成抑制剂，具有抗肿瘤活性。Lycorine hydrochloride 能有效抑制 Hey1B 细胞的有丝分裂增殖 (IC50为 1.2 μM)。 |
| IC50和靶点: | |
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Lamoral-Theys. D., et al.: J. Med. Chem., 52, 6244 (2009)
Cao, Z.F., et al.: Toxicol. Lett., 218, 174 (2013)
Brunhofer, G., et al.: Bioorg. med. Chem., 20, 6669 (2012)
