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Glabridin

Cat. No.:YN251481

  • CAS No. :59870-68-7

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    • 参考文献
    • 产品名称: Glabridin
      CAS No.: 59870-68-7
      Chemical Name: 4-[(3R)-3,4-dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-3-benzenediol
      Synonyms:光甘草定
      分子量:324.37
      分子式:C₂₀H₂₀O₄
      SMILES:OC1=CC=C([C@H]2CC3=CC=C4C(C=CC(C)(C)O4)=C3OC2)C(O)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Glabridin 是从Glycyrrhiza glabra中分到的异黄烷类,能够结合并激活PPARγ,EC50值为 6115 nM。Glabridin 具有抗氧化、抗菌、抗肾炎、抗糖尿病、抗肿瘤、抗炎、抗骨质疏松、保护心血管、保护神经、清除自由基等作用。
      IC50和靶点: [{name:"PPARγ:6.1 μM (EC50)"}]
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Wang, L., Yang, R., Yuan, B., et al.The antiviral and antimicrobial activities of licorice, a widely-used Chinese herbActa Pharm. Sin. B5(4),310-315(2015)

      Ming, L.J., and Yin, A.C.Therapeutic effects of glycyrrhizic acidNat. Prod. Commun.8(3),415-418(2013)

      Lee, K.J., Oh, Y.C., Cho, W.K., et al.Antioxidant and anti-inflammatory activity determination of one hundred kinds of pure chemical compounds using offline and online screening HPLC assayEvid. Based Complement. Alternat. Med.,165457(2015)

      Simmler, C., Pauli, G.F., and Chen, S.-N.Phytochemistry and biological properties of glabridinFitoterapia90,160-184(2013)

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