(Z)-Ligustilide
Cat. No.：YN251483
| 产品名称: | (Z)-Ligustilide |
| CAS No.: | 81944-09-4 |
| Chemical Name: | 3Z-butylidene-4,5-dihydro-1(3H)-isobenzofuranone |
| Synonyms: | 藁本内酯 |
| 分子量: | 190.24 |
| 分子式: | C₁₂H₁₄O₂ |
| SMILES: | O=C1O/C(C2=C1C=CCC2)=C\CCC.[(Z)] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (Z)-Ligustilide 是从Ligusticum chuanxiong Hort中提取的，具有抗菌和抗真菌活性，抗真菌评分为 5.6。_x000D_(Z)-Ligustilide 抑制 FATP5 和 DGAT 的表达，抑制小鼠脂肪酸的摄取和酯化，具有研究非酒精性脂肪性肝病 (NAFLD) 的潜力。 |
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Gijbels, M.J.M., Fischer, F.C., Scheffer, J.J.C., et al.Phthalides in roots of Anethum graveolens and Todaroa montanaScientia Pharmaceutica51(4),414-417(1983)
Qi, H., Jiang, Z., Wang, C., et al.Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damagesOncotarget8(17),29300-29317(2017)
Wang, Y.-R., Xu, H., Tao, M., et al.Ligustilide relieves complete Freund's adjuvant-induced mechanical hyperalgesia through inhibiting the activation of spinal c-Jun N-terminal kinase/c-Jun pathway in ratsPharmacogn. Mag.13(52),634-638(2017)
Xiao, W., Yu, A., Liu, D., et al.Ligustilide treatment promotes functional recovery in a rat model of spinal cord injury via preventing ROS productionInt. J. Clin. Exp. Pathol.8(10),12005-12013(2015)
Peng, B., Zhao, P., Lu, Y.-P., et al.Z-ligustilide activates the Nrf2/HO-1 pathway and protects against cerebral ischemia-reperfusion injury in vivo and in vitroBrain Res.1520,168-177(2013)
