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Trigonelline chloride

Cat. No.:YN251485

  • CAS No. :6138-41-6

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Trigonelline chloride
      CAS No.: 6138-41-6
      Chemical Name: 3-carboxy-1-methyl-pyridinium, monochloride
      Synonyms:Trigonelline hydrochloride
      分子量:173.60
      分子式:C₇H₈ClNO₂
      SMILES:C[N+]1=CC(C(O)=O)=CC=C1.[Cl-]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Trigonelline chloride 是一种大量存在于咖啡中并且具有潜在抗糖尿病活性的生物碱。Trigonelline chloride 具有抗HSV-1,抗菌和抗真菌活性。
      IC50和靶点:
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    • Choi, M., Mukherjee, S., and Yun, J.W.Trigonelline induces browning in 3T3-L1 white adipocytesPhytother Res.35(2),1113-1124(2021)

      Zhang, W., Zhang, Y., Chen, S., et al.Trigonelline, an alkaloid from Leonurus japonicus Houtt., suppresses mast cell activation and OVA-induced allergic asthmaFront. Pharmacol.12,687970(2021)

      Li, Y., Li, Q., Wang, C., et al.Trigonelline reduced diabetic nephropathy and insulin resistance in type 2 diabetic rats through peroxisome proliferator-activated receptor-γExp. Ther. Med.18(2),1331-1337(2019)

      Sharma, L., Lone, N.A., Knott, R.M., et al.Trigonelline prevents high cholesterol and high fat diet induced hepatic lipid accumulation and lipo-toxicity in C57BL/6J mice, via restoration of hepatic autophagyFood Chem. Toxicol.121,283-296(2018)

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