Corilagin
Cat. No.：YN251489
| 产品名称: | Corilagin |
| CAS No.: | 23094-69-1 |
| Chemical Name: | cyclic 3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1-(3,4,5-trihydroxybenzoate)-β-D-glucopyranose |
| Synonyms: | 柯里拉京 |
| 分子量: | 634.45 |
| 分子式: | C₂₇H₂₂O₁₈ |
| SMILES: | OC1=C(C2=C(C(OC[C@H]3O[C@@H](OC(C4=CC(O)=C(O)C(O)=C4)=O)[C@@H](O)[C@@H]([C@H]3O)OC5=O)=O)C=C(O)C(O)=C2O)C5=CC(O)=C1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Corilagin 是一种鞣酸，可从Caesalpinia coriaria(Jacq.) 分离出来。Corilagin 抑制 RNA 肿瘤病毒逆转录酶的活性。Corilagin 抑制金黄色葡萄球菌的生长，MIC 为 25 μg/mL。Corilagin 对肝癌和卵巢癌具有良好的抗肿瘤活性，而对正常细胞和组织的毒性很低。 |
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Abe, I., Kashiwagi, Y., Noguchi, H., et al.Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidaseJ. Nat. Prod.64(8),1010-1014(2001)
Gambari, R., Borgatti, M., Lampronti, I., et al.Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cellsInt. Immunopharmacol.13(3),308-315(2012)
Xiao, H.T., Lin, C.Y., Ho, D.H.H., et al.Inhibitory effect of the gallotannin corilagin on dextran sulfate sodium-induced murine ulcerative colitisJ. Nat. Prod.76(11),2120-2125(2013)
Jia, L., Jin, H., Zhou, J., et al.A potential anti-tumor herbal medicine, corilagin, inhibits ovarian cancer cell growth through blocking the TGF-β signaling pathwaysBMC Complement. Altern. Med.13,33(2013)
Gambari, R., Hau, D.K.P., Wong, W.Y., et al.Sensitization of Hep3B hepatoma cells to cisplatin and doxorubicin by corilaginPhytother. Res.28(5),781-783(2014)
