Usnic acid
Cat. No.：YN251513
| 产品名称: | Usnic acid |
| CAS No.: | 125-46-2 |
| Chemical Name: | 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2H,9bH)-dibenzofurandione |
| Synonyms: | 松萝酸 |
| 分子量: | 344.32 |
| 分子式: | C₁₈H₁₆O₇ |
| SMILES: | O=C(C1(C)C(OC2=C(C(C)=O)C(O)=C(C)C(O)=C12)=C3)C(C(C)=O)C3=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Usnic acid 是地衣次生代谢产物，具有独特的二苯并呋喃骨架。Usnic acid 具有优异的抗癌和抗菌性能。Usnic acid 通过降低 NFATc1 的转录和翻译表达，显著抑制 RANKL 介导的破骨细胞的形成和功能。 |
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Odabasoglu, F., Cakir, A., Suleyman, H., et al.Gastroprotective and antioxidant effects of usnic acid on indomethacin-induced gastric ulcer in ratsJ. Ethnopharmacol.103(1),59-65(2006)
Elo, H., Matikainen, J., and Pelttari, E.Potent activity of the lichen antibiotic (+)-usnic acid against clinical isolates of vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureusNaturwissenschaften94(6),465-468(2007)
Araújo, A.A., de Melo, M.G., Rabelo, T.K., et al.Review of the biological properties and toxicity of usnic acidNat. Prod. Res.29(23),2167-2180(2015)
Fournet, A., Ferreira, M.-E., Rojas de Arias, A., et al.Activity of compounds isolated from Chilean lichens against experimental cutaneous leishmaniasisComp. Biochem. Physiol.116(1),51-54(1997)
Bačkorová, M., Bačkor, M., Mikeš, J., et al.Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acidToxicol. In Vitro25(1),37-44(2011)
