Amentoflavone
Cat. No.：YN251514
CAS No. ：1617-53-4
| 产品名称: | Amentoflavone |
| CAS No.: | 1617-53-4 |
| Chemical Name: | 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 穗花杉双黄酮; Didemethyl-ginkgetin |
| 分子量: | 538.46 |
| 分子式: | C₃₀H₁₈O₁₀ |
| SMILES: | O=C1C=C(C2=CC=C(O)C=C2)OC3=C(C4=CC(C5=CC(C6=C(O)C=C(O)C=C6O5)=O)=CC=C4O)C(O)=CC(O)=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 穗花杉双黄酮 (Amentoflavone) 是一种天然的双黄酮类化合物，具有很多生物活性，包括抗炎、抗氧化、神经保护等作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Hwang, J.H., Choi, H., Woo, E.-R., et al.Antibacterial effect of amentoflavone and its synergistic effect with antibioticsJ. Microbiol. Biotechnol.23(7),953-958(2013)
Yu, S., Yan, H., Zhang, L., et al.A Review on the phytochemistry, pharmacology, and pharmacokinetics of amentoflavone, a naturally-occurring biflavonoid.Molcecules16;22(2),(2017)
Lee, S., Kim, H., Kang, J.-W., et al.The biflavonoid amentoflavone induces apoptosis via suppressing E7 expression, cell cycle arrest at sub-G₁ phase, and mitochondria-emanated intrinsic pathways in human cervical cancer cellsJ. Med. Chem.14(7),808-816(2011)
Zhang, Z., Sun, T., Niu, J.-g., et al.Amentoflavone protects hippocampal neurons: anti-inflammatory, antioxidative, and antiapoptotic effectsNeural. Regen. Res.10(7),1125-1133(2015)
Lin, Y.-M., Flavin, M.T., Schure, R., et al.Antiviral activities of biflavonoidsPlanta. Med.65(2),120-125(1999)
Na, M., Kim, K.A., Oh, H., et al.Protein tyrosine phosphatase 1B inhibitory activity of amentoflavone and its cellular effect on tyrosine phosphorylation of insulin receptorsBiol. Pharm. Bull.30(2),379-381(2007)
Ishola, I.O., Chatterjee, M., Tota, S., et al.Antidepressant and anxiolytic effects of amentoflavone isolated from Cnestis ferruginea in micePharmacol. Biochem. Behav.103(2),322-331(2012)
