Isoalantolactone
Cat. No.：YN251531
CAS No. ：470-17-7
| 产品名称: | Isoalantolactone |
| CAS No.: | 470-17-7 |
| Chemical Name: | (3aR,4aS,8aR,9aR)-decahydro-8a-methyl-3,5-bis(methylene)-naphtho[2,3-b]furan-2(3H)-one |
| Synonyms: | 异土木香内酯; (+) |
| 分子量: | 232.32 |
| 分子式: | C₁₅H₂₀O₂ |
| SMILES: | O=C(O[C@@](C[C@@]1(C)CCC2)([H])[C@]3([H])C[C@@]1([H])C2=C)C3=C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Isoalantolactone 是一种烷化剂，用作细胞凋亡 (apoptosis) 诱导剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Konishi, T., Shimada, Y., Nagao, T., et al.Antiproliferative sesquiterpene lactones from the roots of Inula heleniumBiol. Pharm. Bull.25(10),1370-1372(2002)
Khan, M., Ding, C., Rasul, A., et al.Isoalantolactone induces reactive oxygen species mediated apoptosis in pancreatic carcinoma PANC-1 cellsInt. J. Biol. Sci.8(4),533-547(2012)
Qiu, J., Luo, M., Wang, J., et al.Isoalantolactone protects against Staphylococcus aureus pneumoniaFEMS Microbiol. Lett.324(2),147-155(2011)
He, G., Zhang, H., Chen, Y., et al.Isoalantolactone inhibits LPS-induced inflammation via NF-κB inactivation in peritoneal macrophages and improves survival in sepsisBiomed. Pharmacother.90,598-607(2017)
