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Robinetin

Cat. No.:YN251550

  • CAS No. :490-31-3

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    • 生物活性
    • 参考文献
    • 产品名称: Robinetin
      CAS No.: 490-31-3
      Chemical Name: 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one
      Synonyms:3,3',4',5',7-Pentahydroxyflavone
      分子量:302.24
      分子式:C₁₅H₁₀O₇
      SMILES:O=C1C(O)=C(C2=CC(O)=C(O)C(O)=C2)OC3=CC(O)=CC=C13
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Robinetin (3,3',4',5',7-Pentahydroxyflavone) 是一种黄酮类化合物,具有抗真菌、抗病毒、抗菌、抗突变和抗氧化活性。Robinetin 还可以抑制脂质过氧化和蛋白质糖基化。
      IC50和靶点:
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    • Charlesworth, E.H., and Robinson, R.Anthoxanthins. Part XIII. Synthesis of a colouring matter of Robinia pseudacaciaJ. Chem. Soc.,268-270(1933)

      Hodnick, W.F., Duval, D.L., and Pardini, R.S.Inhibition of mitochondrial respiration and cyanide-stimulated generation of reactive oxygen species by selected flavonoidsBiochem. Pharmacol.47(3),573-580(1994)

      Hyun, J., Woo, Y., Hwang, D.-S., et al.Relationships between structures of hydroxyflavones and their antioxidative effectsBioorg. Med. Chem. Lett.20(18),5510-5513(2010)

      Boušová, I., Hájek, J., Dršata, J., et al.Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferaseXenobiotica42(9),872-879(2012)

      van Zanden, J.J., Wortelboer, H.M., Bijlsma, S., et al.Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2Biochem. Pharmacol.69(4),699-708(2005)

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