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Pogostone

Cat. No.:YN251555

  • CAS No. :23800-56-8

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Pogostone
      CAS No.: 23800-56-8
      Chemical Name: 4-hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)-2H-pyran-2-one
      Synonyms:DHELWANGIN,广藿香酮
      分子量:224.25
      分子式:C₁₂H₁₆O₄
      SMILES:O=C1C(C(CCC(C)C)=O)=C(O)C=C(C)O1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Pogostone 从薄荷中分离出,具有抗菌和抗癌活性。 Pogostone 抑制革兰氏阴性菌和革兰氏阳性菌,也表现出对干燥杆菌的抑制作用,MIC值为 0.098 µg /ml。 Pogostone 诱导细胞凋亡 (apoptosis) 和自噬 (autophagy)。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Yi, Y.-Y., He, J.-J., Su, J.-Q., et al.Synthesis and antimicrobial evaluation of pogostone and its analoguesFitoterapia84,135-139(2013)

      Li, Y.-C., Liang, H.-C., Chen, H.-M., et al.Anti-Candida albicans activity and pharmacokinetics of pogostone isolated from Pogostemonis HerbaPhytomedicine20(1),77-83(2012)

      Huang, S.-H., Xian, J.-D., Kong, S.-Z., et al.Insecticidal activity of pogostone against Spodoptera litura and Spodoptera exigua (Lepidoptera: Noctuidae)Pest Manag. Sci.70(3),510-516(2014)

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