Afzelin
Cat. No.：YN251558
| 产品名称: | Afzelin |
| CAS No.: | 482-39-3 |
| Chemical Name: | 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | Kaempferol-3-O-rhamnoside |
| 分子量: | 432.38 |
| 分子式: | C₂₁H₂₀O₁₀ |
| SMILES: | O=C1C(O[C@H]2[C@@H]([C@@H]([C@H]([C@H](C)O2)O)O)O)=C(C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C14 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Afzelin (Kaempferol-3-O-rhamnoside) 是一种在鱼腥草 (Houttuynia cordata) 中发现的黄酮醇糖苷，广泛用于制备抗菌剂，解热剂，解毒剂和抗炎剂。 Afzelin 减弱线粒体损伤，增强线粒体生物合成，降低线粒体相关蛋白，帕金和 PTEN 诱导的假定激酶 1 (putative kinase 1)的水平。Afzelin 可提高 D-半乳糖胺 (GalN)/LPS 处理的小鼠的存活率，降低丙氨酸氨基转移酶和促炎细胞因子的血清水平。 |
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Tatsimo, S.J.N., Tamokou, J.d.D., Havyarimana, L., et al.Antimicrobial and antioxidant activity of kaempferol rhamnoside derivatives from Bryophyllum pinnatumBMC Res. Notes5,158(2012)
Kim, Y.-K., Kim, Y.S., Choi, S.U., et al.Isolation of flavonol rhamnosides from Loranthus tanakae and cytotoxic effect of them on human tumor cell linesArch. Pharm. Res.27(1),44-47(2004)
Chung, M.J., Pandey, R.P., Choi, J.W., et al.Inhibitory effects of kaempferol-3-O-rhamnoside on ovalbumin-induced lung inflammation in a mouse model of allergic asthmaInt. Immunopharmacol.25(2),302-310(2015)
