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Artemisic acid

Cat. No.:YN251569

  • CAS No. :80286-58-4

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    • 参考文献
    • 产品名称: Artemisic acid
      CAS No.: 80286-58-4
      Chemical Name: 1R,2,3,4R,4aS,5,6,8aR-octahydro-4,7-dimethyl-α-methylene-1-naphthaleneacetic acid
      Synonyms:青蒿酸; Qing Hao acid; Artemisinic acid; Arteannuic acid
      分子量:234.33
      分子式:C₁₅H₂₂O₂
      SMILES:O=C(O)C([C@@H]1CC[C@@H](C)[C@]2([H])CCC(C)=C[C@]12[H])=C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Artemisinic acid (Qing Hao acid) 是黄花蒿中分离得到的一种倍半萜,具有多种药理活性,如抗疟活性、抗肿瘤活性、解热作用、抗菌活性、化感作用、抗脂肪生成作用。
      IC50和靶点:
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    • Misra, L.N., Ahmad, A., and Thakur, R.S.Crystal structure of artemisinic acid: A possible biogenetic precursor of antimalarial artemisinin from Artemisia annuaJ. Nat. Prod.56(2),215-219(1993)

      Turconi, J., Griolet, F., Guevel, R., et al.Semisynthetic artemisinin, the chemical path to industrial productionOrg. Process Res. Dev.18(3),417-422(2014)

      Lee, J., Kim, M.-H., Lee, J.-H., et al.Artemisinic acid is a regulator of adipocyte differentiation and C/EBP δ expressionJ. Cell. Biochem.113(7),2488-2499(2012)

      Lee, J., Lee, J., Jung, E., et al.Artemisinic acid inhibits melanogenesis through downregulation of C/EBP α-dependent expression of HMG-CoA reductase geneFood Chem. Toxicol.51,225-230(2013)

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