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Pleuromutilin

Cat. No.:YN251591

  • CAS No. :125-65-5

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    • 生物活性
    • 参考文献
    • 产品名称: Pleuromutilin
      CAS No.: 125-65-5
      Chemical Name: 2-hydroxy-acetic acid, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
      Synonyms:截短侧耳素; Drosophilin B; Mutilin 14-glycolate
      分子量:378.50
      分子式:C₂₂H₃₄O₅
      SMILES:C[C@@H]([C@@H]([C@@](C)(C[C@H]1OC(CO)=O)C=C)O)C(CC[C@H]2C)(CCC3=O)[C@]3([H])C21C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Pleuromutilin (Drosophilin B) 能够通过绑定细菌的核糖体亚基50S抑制细菌的蛋白合成。
      IC50和靶点:
      In Vitro:
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    • Kilaru, S., Collins, C.M., Hartley, A.J., et al.Establishing molecular tools for genetic manipulation of the pleuromutilin-producing fungus Clitopilus passeckerianusAppl. Environ. Microbiol.75(22),7196-7204(2009)

      Long, K.S., Hansen, L.H., Jakobsen, L., et al.Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase centerAntimicrob. Agents and Chemother.50(4),1458-1462(2006)

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