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Pinosylvin

Cat. No.:YN251599

  • CAS No. :22139-77-1

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    • 生物活性
    • 参考文献
    • 产品名称: Pinosylvin
      CAS No.: 22139-77-1
      Chemical Name: 5-[(1E)-2-phenylethenyl]-1,3-benzenediol
      Synonyms:5-Styrylresorcinol,银松素,3,5-stilbenediol
      分子量:212.24
      分子式:C₁₄H₁₂O₂
      SMILES:OC1=CC(/C=C/C2=CC=CC=C2)=CC(O)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Pinosylvin 是从Pinus spp的心材中分离出来的一种感染前的类苯乙烯类毒素,具有抗菌 (anti-bacterial) 活性。 Pinosylvin 是一种白藜芦醇的类似物,可以诱导白血病细胞凋亡 (apoptosis) 和自噬 (autophapy)。
      IC50和靶点:
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    • Alvarez-Novoa, J.C., Erdtman, H., and Lindstedt, G.Constituents of pine heartwood. XIX. The heartwood of Pinus pinea, Pinus pinaster, Pinus halepensis, and Pinus nigraActa Chem. Scand.4(3),444-447(1950)

      Modi, S., Yaluri, N., Kokkola, T., et al.Plant-derived compounds strigolactone GR24 and pinosylvin activate SIRT1 and enhance glucose uptake in rat skeletal muscle cellsSci. Rep.7(1),17606(2017)

      Seppänen, S.K., Syrjälä, L., von Weissenberg, K., et al.Antifungal activity of stilbenes in in vitro bioassays and in transgenic Populus expressing a gene encoding pinosylvin synthasePlant Cell. Rep.22(8),584-593(2004)

      Park, E.-J., Park, H.-J., Chung, H.-J., et al.Antimetastatic activity of pinosylvin, a natural stilbenoid, is associated with the suppression of matrix metalloproteinasesJ. Nutr. Biochem.23(8),946-952(2012)

      Mačičková, T., Drábiková, K., Nosál', R., et al.In vivo effect of pinosylvin and pterostilbene in the animal model of adjuvant arthritisNeuro. Endocrinol. Lett.31(Suppl 2),91-95(2013)

      Sullivan, T.P., Crump, D.R., Wieser, H., et al.Influence of the plant antifeedant, pinosylvin, on suppression of feeding by snowshoe haresJ. Chem. Ecol.18(7),1151-1164(1992)

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