(E)-Methyl 4-coumarate
Cat. No.:YN251607
CAS No. :19367-38-5
产品名称: | (E)-Methyl 4-coumarate |
CAS No.: | 19367-38-5 |
Chemical Name: | 3-(4-hydroxyphenyl)-2-propenoic acid, methyl ester |
Synonyms: | Methyl trans-p-coumarate |
分子量: | 178.18 |
分子式: | C₁₀H₁₀O₃ |
SMILES: | O=C(OC)/C=C/C1=CC=C(O)C=C1.[E] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate) 在几种植物中发现,如葱 (Allium cepa) 或 noni (Morinda citrifoliaL.) 叶中。(E)-Methyl 4-coumarate 与 Carnosic Acid 联用可诱导细胞凋亡,杀死急性髓性白血病细胞,但不能杀死正常的外周血单核细胞。(E)-Methyl 4-coumarate 具有抗氧化和抗菌活性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Trachtenberg, A., Muduli, S., Sidoryk, K., et al.Synergistic cytotoxicity of methyl 4-hydroxycinnamate and carnosic acid to acute myeloid leukemia cells via calcium-dependent apoptosis inductionFront. Pharmacol.10,507(2019)
Sudi, S., Ali, A.H., Basir, R., et al.A derivative of cinnamic acid, methyl-4-hydroxycinnamate modules inflammatory cytokine levels in malaria-infected mice through inhibition of GSK3βMalays. Appl. Biol.47(3),153-157(2018)
Wan, C., Yuan, T., Cirello, A.L., et al.Antioxidant and α-glucosidase inhibitory phenolics isolated from highbush blueberry flowersFood Chem.135(3),1929-1937(2012)
Jung, Y.-J., Park, J.-H., Seo, K.-H., et al.Phenolic compounds from the stems of Zea mays and their pharmacological activityJ. Korean Soc. Appl. Biol. Chem.57(3),379-385(2014)