15-Acetoxyscirpenol
Cat. No.：YN251682
| 产品名称: | 15-Acetoxyscirpenol |
| CAS No.: | 2623-22-5 |
| Chemical Name: | 12,13-epoxy-trichothec-9-ene-3α,4β,15-triol, 15-acetate |
| Synonyms: | |
| 分子量: | 308.37 |
| 分子式: | C₁₇H₂₄O₅ |
| SMILES: | O[C@@H]1C[C@@]2([C@]3(CCC(C)=C[C@]3(O[C@H]1[C@]24OC4)[H])COC(C)=O)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 15-acetoxyscirpenol，acetoxyscirpenol 霉菌毒素 (ASMs) 之一，通过激活 caspase-3 以外的其他caspases，以剂量依赖性方式抑制 Jurkat T 细胞生长，诱导细胞凋亡。 |
| IC50和靶点: | |
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Peraica, M., Radić, B., Lucić, A., et al.Toxic effects of mycotoxins in humansBull. World Health Ogan.77(9),754-766(1999)
Lee, D.H., Park, T., and Kim, H.W.Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxinsBiol. Pharm. Bull.29(4),648-654(2006)
