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Virginiamycin M1

Cat. No.:YN251684

  • CAS No. :21411-53-0

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    • 生物活性
    • 参考文献
    • 产品名称: Virginiamycin M1
      CAS No.: 21411-53-0
      Chemical Name: (3R,4R,5E,10E,12E,14S)-8,9,14,15,24,25-hexahydro-14-hydroxy-4,12-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
      Synonyms:Pristinamycin IIA; Ostreogrycin A
      分子量:525.59
      分子式:C₂₈H₃₅N₃O₇
      SMILES:O=C1N2C(C(O[C@@H]([C@@H](/C=C/C(NC/C=C/C(C)=C/[C@H](CC(CC3=NC1=CO3)=O)O)=O)C)C(C)C)=O)=CCC2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Pristinamycin IIA (RP 12536) 是一种大环内酯类抗生素, 来源于Streptomyces pristinaespiralis,是 streptogramin A 组抗生素。
      IC50和靶点:
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      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Fair, R.J., and Tor, Y.Antibiotics and bacterial resistance in the 21st centuryPerspect. Medicin. Chem.6,25-64(2014)

      Kehrenberg, C., Cuny, C., Strommenger, B., et al.Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfrAntimicrob. Agents Chemother.53(2),779-781(2009)

      Parfait, R., and Cocito, C.Lasting damage to bacterial ribosomes by reversibly bound virginiamycin MProc. Natl. Acad. Sci. USA77(9),5492-5496(1980)

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