Valinomycin
Cat. No.：YN251688
CAS No. ：2001-95-8
| 产品名称: | Valinomycin |
| CAS No.: | 2001-95-8 |
| Chemical Name: | 3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaaza-cyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecaone |
| Synonyms: | NSC 122023 |
| 分子量: | 1111.32 |
| 分子式: | C₅₄H₉₀N₆O₁₈ |
| SMILES: | O=C([C@@H](C(C)C)NC([C@@H](C(C)C)OC([C@H](C(C)C)NC([C@H](C)OC([C@@H](C(C)C)NC([C@@H](C(C)C)OC([C@H](C(C)C)NC([C@H](C)OC([C@@H](C(C)C)NC([C@@H](C(C)C)OC([C@H](C(C)C)N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)O[C@@H](C)C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Valinomycin (NSC 122023) 是一种环状缩酚肽类抗生素，最初从Streptomyces fulvissimus中分离得到，是一种钾离子选择性运输载体。Valinomycin (NSC 122023) 通过影响生物膜抑制淋巴细胞的扩增，能诱导 CHO 细胞凋亡。Valinomycin 诱导 PINK1 激活，促进 Parkin 在 Ser65 位点磷酸化。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Abdalah, R., Wei, L., Francis, K., et al.Valinomycin-induced apoptosis in Chinese hamster ovary cellsNeurosci. Lett.405(1-2),68-73(2006)
