Alamethicin
Cat. No.：YN251695
| 产品名称: | Alamethicin |
| CAS No.: | 27061-78-5 |
| Chemical Name: | (3S,12R)-1-((S)-1-((6S,12S,15S,21S,30S)-1-((R)-1-(2-acetamido-2-methylpropanoyl)pyrrolidin-2-yl)-15-(3-amino-3-oxopropyl)-30-isobutyl-21-isopropyl-3,3,6,9,9,12,18,18,24,24,33,33-dodecamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaoxo-2,5,8,11,14,17,20,23,26, |
| Synonyms: | 丙甲菌素 |
| 分子量: | 1964.34 |
| 分子式: | C₉₂H₁₅₀N₂₂O₂₅ |
| SMILES: | [Alamethicin] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Alamethicin 是从Trichoderma viride中分离得到的一种通道形成抗生素肽，可诱导电压门控电导。 |
| IC50和靶点: | |
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Maischak, H., Zimmermann, M.R., Felle, H.H., et al.Alamethicin-induced electrical long distance signaling in plantsPlant Signal. Behav.5(8),988-990(2010)
Kessel, A., Cafiso, D.S., and Ben-Tal, N.Continuum solvent model calculations of alamethicin-membrane interactions: Thermodynamic aspectsBiophys. J.78(2),571-583(2000)
Pan, J., Tristram-Nagle, S., and Nagle, J.F.Alamethicin aggregation in lipid membranesJ. Membr. Biol.231(1),1-36(2009)
Jones, L.R., Maddock, S.W., and Besch, H.R., Jr.Unmasking effect of alamethicin on the (Na+,K+)-ATPase, β-adrenergic receptor-coupled adenylate cyclase, and cAMP-dependent protein kinase activities of cardiac sarcolemmal vesiclesJ. Biol. Chem.255(20),9971-9980(1980)
Walsky, R.L., Bauman, J.N., Bourcier, K., et al.Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: Altered alamethicin concentration and utility to screen for UGT inhibitorsDrug Metab. Dispos.40(5),1051-1065(2012)
