Sterigmatocystine
Cat. No.：YN251701
| 产品名称: | Sterigmatocystine |
| CAS No.: | 10048-13-2 |
| Chemical Name: | (3aR,12cS)-3a,12c-dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one |
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| 分子量: | 324.28 |
| 分子式: | C₁₈H₁₂O₆ |
| SMILES: | O=C1C2=C(OC3=C1C(O)=CC=C3)C4=C(O[C@]5([H])[C@@]4([H])C=CO5)C=C2OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sterigmatocystine 是黄曲霉素的前体，是由Aspergillus versicolor产生的一种霉菌素。 Sterigmatocystine 是 G1 期和 DNA 合成的抑制剂，用于抑制 p21 活性。Sterigmatocystine 对动物发育具有致畸和致癌作用。 |
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Kusunoki, M., Misumi, J., Shimada, T., et al.Long-term administration of the fungus toxin, sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbilsEnviron. Health Prev. Med.16(4),224-231(2011)
Schroeder, H.W., and Kelton, W.H.Production of sterigmatocystin by some species of the genus Aspergillus and its toxicity to chicken embryos.Appl. Microbiol.30(4),589-591(1975)
Fujii, K., Kurata, H., Odashima, S., et al.Tumor induction by a single subcutaneous injection of sterigmatocystin in newborn miceCancer Res.36(5),1615-1618(1976)
