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Helvolic acid

Cat. No.:YN251703

  • CAS No. :29400-42-8

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Helvolic acid
      CAS No.: 29400-42-8
      Chemical Name: (4α,6β,8α,9β,13α,14β,16β,17Z)-6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
      Synonyms:Fumigacin
      分子量:568.70
      分子式:C₃₃H₄₄O₈
      SMILES:C[C@@H]([C@]1([H])[C@H](OC(C)=O)C([C@]([C@@](C[C@@H]/2OC(C)=O)3C)4C)=O)C(C=C[C@]1(C)[C@]4([H])CC[C@@]3([H])C2=C(C(O)=O)/CC/C=C(C)\C)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Helvolic acid (Fumigacin) 是从真菌中得到的抗生素,有效作用于革兰氏阳性菌。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Chain, E., Florey, H.W., Jennings, M.A., et al.Helvolic acid, an antibiotic produced by Apergillus funigatus, mut. helvola YuillBr. J. Exp. Pathol.24(3),108-119(1943)

      Ratnaweera, P.B., Williams, D.E., de Silva, E.D., et al.Helvolic acid, an antibacterial nortriterpenoid from a fungal endophyte, Xylaria sp. of orchid Anoectochilus setaceus endemic to Sri LankaMycology5(1),23-28(2014)

      Qin, L., Li, B., Guan, J., et al.In vitro synergistic antibacterial activities of helvolic acid on multi-drug resistant Staphylococcus aureusNat. Prod. Res.23(4),309-318(2009)

      Xiao, J.-H., Zhang, Y., Liang, G.-Y., et al.Synergistic antitumor efficacy of antibacterial helvolic acid from Cordyceps taii and cyclophosphamide in a tumor mouse modelExp. Biol. Med. (Maywood)242(2),214-222(2017)

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