Aureothricin
Cat. No.：YN251705
CAS No. ：574-95-8
| 产品名称: | Aureothricin |
| CAS No.: | 574-95-8 |
| Chemical Name: | N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-propanamide |
| Synonyms: | 金色抗霉素 |
| 分子量: | 242.32 |
| 分子式: | C₉H₁₀N₂O₂S₂ |
| SMILES: | CN1C2=CSSC2=C(C1=O)NC(CC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aureothricin 是一种二硫吡咯酮类 (DTP) 抗生素，首次是从链霉菌中获得，具有相对广谱的抗菌活性。Aureothricin 能抑制人脐静脉内皮细胞 (HUVECs) 与玻连蛋白的黏附。 |
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Li, B., Wever, W.J., Walsh, C.T., et al.Dithiolopyrrolones: Biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibioticsNat. Prod. Rep.31(7),905-923(2014)
Minamiguchi, K., Kumagai, H., Masuda, T., et al.Thiolutin, an inhibitor of HUVEC adhesion to vitronectin, reduces paxillin in HUVECs and suppresses tumor cell-induced angiogenesisInt. J. Cancer93(3),307-316(2001)
