Penicillic acid
Cat. No.：YN251710
| 产品名称: | Penicillic acid |
| CAS No.: | 90-65-3 |
| Chemical Name: | 3-methoxy-5-methyl-4-oxo-2,5-hexadienoic acid |
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| 分子量: | 170.16 |
| 分子式: | C₈H₁₀O₄ |
| SMILES: | C=C(C)C(/C(OC)=C/C(O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Penicillic acid 是由几种曲霉菌和青霉菌产生的一种聚酮化合物霉菌毒素，在体外对大鼠肺泡巨噬细胞 (AM) 具有细胞毒性。Penicillic acid 通过阻断 caspase-8 自我加工来抑制 Fas 配体诱导的细胞凋亡。 |
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Rasmussen, T.B., Skindersoe, M.E., Bjarnsholt, T., et al.Identity and effects of quorum-sensing inhibitors produced by Penicillium speciesMicrobiology151,1325-1340(2005)
Bando, M., Hasegawa, M., Tsuboi, Y., et al.The mycotoxin penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 in death-inducing signaling complexJ. Biol. Chem.278(8),5786-5793(2003)
