KT5720
Cat. No.：YN251714
CAS No. ：108068-98-0
| 产品名称: | KT5720 |
| CAS No.: | 108068-98-0 |
| Chemical Name: | 2,3,9,10,11,12-hexahydro-10S-hydroxy-9-methyl-1-oxo-9R,12S-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, hexyl ester |
| Synonyms: | KT5720 |
| 分子量: | 537.61 |
| 分子式: | C₃₂H₃₁N₃O₅ |
| SMILES: | C[C@@]12N3C4=C(C5=CC=CC=C35)C(CNC6=O)=C6C7=C4N(C8=CC=CC=C87)[C@@](C[C@@]2(O)C(OCCCCCC)=O)([H])O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | KT5720 是一种能透过细胞的、有效的、特异性的、可逆的、ATP 竞争性的蛋白酶 K (PKA)的抑制剂，其Ki值为 60 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Kase, H., Iwahashi, K., Nakanishi, S., et al.K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinasesBiochem. Biophys. Res. Commun.142(2),436-440(1987)
Davies, S.P., Reddy, H., Caivano, M., et al.Specificity and mechanism of action of some commonly used protein kinase inhibitorsBiochem. J.351(1),95-105(2000)
Murray, A.J.Pharmacological PKA inhibition: All may not be what it seemsSci. Signal.1(22),(2008)
