Nivalenol
Cat. No.：YN251719
| 产品名称: | Nivalenol |
| CAS No.: | 23282-20-4 |
| Chemical Name: | (3α,4β,7α)-12,13-epoxy-3,4,7,15-tetrahydroxy-trichothec-9-en-8-one |
| Synonyms: | 雪腐镰刀菌烯醇 |
| 分子量: | 312.32 |
| 分子式: | C₁₅H₂₀O₇ |
| SMILES: | CC12C3(CO3)[C@@](O[C@@]4([H])[C@]2(CO)[C@@H](C(C(C)=C4)=O)O)([H])[C@H](O)[C@H]1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nivalenol 是由禾谷镰刀菌 (Fusarium graminearum) 产生的 B 型三氯乙烯毒素 (B trichotecenes toxins)，是农产品中存在的真菌代谢物。Nivalenol 通过caspase依赖性机制和内在的凋亡 (apoptotic)途径诱导细胞死亡。Nivalenol 影响免疫系统，引起呕吐，生长迟缓，生殖障碍并具有血液毒性/骨髓毒性作用。 |
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Yang, Z., Concannon, J., Ng, K.S., et al.Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulationSci. Rep.6,30263(2016)
Yoshizawa, T., and Morooka, N.Studies on the toxic substances in the infected cereals (part 3): Acute toxicities of new trichothecene mycotoxins: Deoxynivalenol and its monoacetateJ. Food Hyg.15(4),261-269(1974)
Poapolathep, A., Ohtsuka, R., Kiatipattanasakul, W., et al.Nivalenol-induced apoptosis in thymus, spleen and Peyer's patches of miceExp. Toxicol. Pathol.53(6),441-446(2002)
