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4-Hydroxycoumarin

Cat. No.:YN251725

  • CAS No. :1076-38-6

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 4-Hydroxycoumarin
      CAS No.: 1076-38-6
      Chemical Name: 4-hydroxy-2H-1-benzopyran-2-one
      Synonyms:4-羟基香豆素
      分子量:162.14
      分子式:C₉H₆O₃
      SMILES:O=C1C=C(O)C2=CC=CC=C2O1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 4-Hydroxycoumarin 是一种香豆素衍生物,最通用的杂环支架之一,常用于各种有机化合物的合成。4-Hydroxycoumarin 具有亲电和亲核性质。4-Hydroxycoumarin 衍生物可以用作抗凝血剂,抗细菌剂,抗真菌剂,抗病毒剂,抗肿瘤剂,抗原虫剂,杀虫剂,抗分枝杆菌剂,抗突变剂,抗氧化剂,抗炎剂,HIV 蛋白酶抑制剂和酪氨酸激酶抑制剂。
      IC50和靶点:
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      In Vivo:
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      Solvent & Solubility:
    • Vickery, M., and Vickery, B.Coumarins and related compounds in members of the ConnaraceaeToxicol. Lett.5(2),115-118(1980)

      Bell, R.G., and Stark, P.Inhibition of prothrombin synthesis and epoxidation of vitamin K1 by anticoagulants in vitroBiochem. Biophys. Res. Commun.72(2),619-625(1976)

      Jung, J.-C., and Park, O.-S.Synthetic approaches and biological activities of 4-hydroxycoumarin derivativesMolecules14(11),4790-4803(2009)

      Chohan, Z.H., Shaikh, A.U., Rauf, A., et al.Antibacterial, antifungal and cytotoxic properties of novel N-substituted sulfonamides from 4-hydroxycoumarinJ. Enzyme Inhib. Med. Chem.21(6),741-748(2006)

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